A pioneering global systematic review has found that the shingles vaccine is linked to an 18% lower risk of stroke or heart attack in adults. The analysis, which combined data from 19 studies including observational research and randomized trials, suggests that vaccination against herpes zoster could offer cardiovascular benefits in addition to preventing the painful viral infection.
The findings indicate potential protective effects not only for older adults but also for younger adults, with cardiovascular risk reduction observed across different age groups. Experts say the effect may be related to lowering inflammation in the body caused by shingles, which can contribute to heart and circulatory problems.
Researchers caution that further studies are needed to confirm causation and understand the mechanisms behind this association. Meanwhile, health authorities such as NHS England are expanding eligibility for the vaccine to include younger adults with weakened immune systems. The research highlights the broader potential of vaccines in preventing both infectious diseases and related cardiovascular complications.
